Cryo-SiN

Ideal Substrate for Cryo-Microscopy

"Our initial findings indicate that viral particles prepared on Cryo-SiN, exhibited greater contrast in comparison to those prepared on holey carbon films under the same conditions. As a result, we were able to calculate 3D reconstructions of viral particles prepared on Cryo-SiN using a fraction of the images required for samples prepared on holey carbon films." Tanner et al. Microscopy & Microanalysis Abstract, 2013

• Avoid substrate degradation seen with carbon grids
• Plasma cleanable to reduce contaminants
• Our proprietary carbon coating may also improve charge dissipation leading to a reduction in beam induced movement
• Large 500um windows provide ~50 x 50um viewing from any orientation at 70 degrees of tilt for tomography